Dr Andrew Spiers

Reader

School School of Applied Sciences

Department Division of Engineering and Food Sciences

Contact info

+44 (0)1382 30 8730

Biography

I am currently a Reader in molecular and environmental microbiology with a particular interest in the evolutionary ecology of bacterial biofilms. I am the Programme Leader for the BSc(Hons) Environmental Science and Technology (EST) undergraduate programme, and lead or contribute to the delivery of teaching for a variety of EST and Biomedical Sciences (BMS) programme modules, as well as running undergraduate Hons research projects. My research group currently includes two PhD students and we regularly host visiting students and internships each year. I am the University’s Environment Theme Leader, a member of the Research Degrees Assessment Panel and our School’s Health and Safety Committee co-chair. I am also a Fellow of the Royal Society of Biology and the Secretary for the Royal Society of Biology in Scotland Council, and a Senior Fellow of Advance HE (formerly the Higher Education Academy).

I completed my undergraduate degree in Zoology and Cell Biology from the University of Auckland in New Zealand, confered in 1986, which was followed by a MSc(Hons) in Cell Biology in 1988 and a PhD in Cellular and Molecular Biology in 1993 at Auckland. Prior to joining Abertay in 2007, I undertook two postdoctoral research positions at the Department of Biochemistry and the Department of Plant Sciences, University of Oxford, a University Research Lectureship at Plant Sciences, and a year as a researcher at the NERC Centre for Hydrology and Ecology (CEH) at Oxford.

My research is currently focussed on the evolutionary ecology of the archetypal Wrinkly Spreader biofilm-former and community biofilm-formation, as well as on the expression of bio-surfactants by environmental pseudomonads, many of which also produce biofilms. This has involved a number of PhD and MbRes students and resulted in a number of primary reserach articles, opinion pieces and reviews. Our work and collaborations have been enabled by funding from NERC, Royal Society of Edinburgh, the ERASMUS programme, and the Nigerian Petroleum Technology Devoplment Fund (PTDF) and Tertiary Education Trust Fund (Tetfund). 

I have been involved in the delivery of teaching across a number of undergraduate and postgraduate programmes since joining Abertay, and have also been involved in programme development and reviews. My current teaching responsibilities include:

  • Programme leader for the BSc(Hons) Environmental Science and Technology (EST) undergraduate programme.
  • Module leader for ENV101 Introduction to Environmental Sciences where I am responsible for lectures, tutorials, the field trip and assessments.
  • Module leader for ENV205 Environment and Human Interactions where I am responsible for lectures, tutorials and assessments.
  • Module leader for ENV409 Environmental Modelling and Climate Change where I am responsible for lectures, tutorials, field trip and assessments.
  • Module leader for LSC201 Molecular Biology and Genetics where I am responsible for lectures, tutorials, laboratories and assessments.
  • Module leader for LSC309 Perspectives and Technologies in the Life Sciences Sector where I am responsible for the module development, lectures, tutorials and assessments.
  • Laboratory demonstrator for LSC203 Medical Microbiology where I am responsible for laboratories and assessments.
  • Moderator for LSC401 Project Research Methods where I am responsible for assessment moderation.
  • Supervisor for LSC402 Honours Projects where I am responsible for project supervision and assessments.

Interests

  • Robyn Jerdan (PhD student). Principal supervisor (Abertay, started 2017).
  • Raji Bamanga (PhD student). Second supervisor (Abertay, started 2016).
  • Kamaluddeen Kabir (PhD). Bioprospecting surfactants produced by Pseudomonas spp. isolated from soil for potential Application in biotechnology. Principal supervisor (Abertay, 2014 – 17). 
  • Habibu Abdu (PhD). Investigating the role of glutathione and glutathione biosynthetic genes in the adaptation of Anopheles gambiae to insecticides. Second supervisor (Abertay, 2013 – 16).
  • Ibrahim Mohammed (PhD). Screening environmental pseudomonads for characteristics suitable for a bio-engineered oil remediation agent. Principal supervisor (Abertay, 2011 – 16).
  • Kimberley McLaughlin (MbRes). Wrinkly Spreaders, wrinkleality and fitness. Principal supervisor (Abertay, 2014 – 16).
  • Patricia Dello Sterpaio (PhD). The impact of bacteria on the biophysics of water retention and flow in soil. Principal supervisor from late 2009 (Abertay, 2009 – 14).
  • Helen Downey (PhD). The development of a transparent soil and its implication in imaging root trajectories and root bacteria interactions. Second (academic) supervisor (Abertay, Joint JHI-Abertay studentship, 2010 – 13).
  • Yvette Udall (MbRes). The evolution of P. fluorescens SBW25 in glass bead column and static microcosms shows an environmental effect on the wrinkleality of Wrinkly Spreader adaptive mutants. Principal supervisor (Abertay, 2012 – 13).
  • Anna Koza (PhD). Adaptation and niche construction by Pseudomonas fluorescens SBW25. Principal supervisor (Abertay, 2008 – 12). 
  • Ayorinde Folorunso (MbRes). Bioinformatics investigation of bacteria cellulose synthesis operons amongst the Proteobacter. Principal supervisor (Abertay, 2011 – 12).
  • Kate Bailey (PhD). Academic supervisor until 2006 (Oxford, Joint CEH-Oxford studentship, 2003 – 7).
  • Stefanie Gehrig (PhD). Adaptation of Pseudomonas fluorescens SBW25 to the air-liquid interface: a study in evolutionary genetics. Academic supervisor from 2004 (Oxford, 2002 – 5).
  • Jacob Malone (PhD). Analysis of the structure-function relationship of WspR, a GGDEF response-regulator. Academic supervisor from 2004 (Oxford, 2002 – 5).

2019

Penetrating the air-liquid interface is the key to colonization and Wrinkly Spreader fitness

Jerdan, R., Kuśmierska, A., Petric, M. & Spiers, A. J. (2019) Penetrating the air-liquid interface is the key to colonization and Wrinkly Spreader fitness. . . .
View in Research Portal

Penetration of the air–liquid interface is key to the Wrinkly Spreader success

Jerdan, R., Kuśmierska, A., White, N. A. . & Spiers, A. J. (2019) Penetration of the air–liquid interface is key to the Wrinkly Spreader success. . . .
View in Research Portal

2018

Differential expression of insecticide resistance genes in Anopheles gambiae from Northern Nigeria

Abdu, H. U., Spiers, A. J., Hapca, S., Dauda, M. M. & Deeni, Y. Y. (2018) Differential expression of insecticide resistance genes in Anopheles gambiae from Northern Nigeria. . . p. S22-S22. .
View in Research Portal

Control of pore geometry in soil microcosms and its effect on the growth and spread of Pseudomonas and Bacillus sp.

Juyal, A., Eickhorst, T., Falconer, R., Baveye, P. C., Spiers, A. & Otten, W. (2018) Control of pore geometry in soil microcosms and its effect on the growth and spread of Pseudomonas and Bacillus sp.. . . .
View in Research Portal

Priming winter wheat seeds with the bacterial quorum sensing signal N-hexanoyl-L-homoserine lactone (C6-HSL) shows potential to improve plant growth and seed yield

Moshynets, O. V., Babenko, L. M., Rogalsky, S. P., Iungin, O. S., Foster, J., Kosakivska, I. V., Potters, G. & Spiers, A. J. (2018) Priming winter wheat seeds with the bacterial quorum sensing signal N-hexanoyl-L-homoserine lactone (C6-HSL) shows potential to improve plant growth and seed yield. . . .
View in Research Portal

Examining c-di-GMP and possible quorum sensing regulation in Pseudomonas fluorescens SBW25

Moshynets, O. V., Foster, D., Karakhim, S. A., McLaughlin, K., Rogalsky, S. P., Rymar, S. Y., Volynets, G. P. & Spiers, A. J. (2018) Examining c-di-GMP and possible quorum sensing regulation in Pseudomonas fluorescens SBW25. . . p. 17-31. .
View in Research Portal

2017

N-acyl-L-homoserine lactones are inter-kingdom signalling molecules controlling quorum sensing in the Gram-negative bacteria and priming plants increasing stress adaptation

Moshynets, O., Babenko, L., Karakhim, S., Kharkhota, M., Kosakivska, I., Rogalsky, S., Shcherbatiuk, M., Suslova, O. & Spiers, A. (2017) N-acyl-L-homoserine lactones are inter-kingdom signalling molecules controlling quorum sensing in the Gram-negative bacteria and priming plants increasing stress adaptation. . . p. 358-358. .
View in Research Portal

Control of pore geometry in soil microcosms and its effect on the growth and spread of Pseudomonas and Bacillus sp.

Otten, W., Juyal, A., Eickhorst, T., Falconer, R., Spiers, A. & Baveye, P. C. (2017) Control of pore geometry in soil microcosms and its effect on the growth and spread of Pseudomonas and Bacillus sp.. . . .
View in Research Portal

High-activity surfactants expressed by Pseudomonas spp. show significant behavioural differences

Kabir, K., Deeni, Y., Mohammed, I. & Spiers, A. (2017) High-activity surfactants expressed by Pseudomonas spp. show significant behavioural differences. . . p. 41-41. .
View in Research Portal

Adaptive radiation of Pseudomonas fluorescens SBW25 in experimental microcosms provides an understanding of the evolutionary ecology and molecular biology of A-L interface biofilm formation

Koza, A., Kuśmierska, A., McLaughlin, K., Moshynets, O. & Spiers, A. J. (2017) Adaptive radiation of Pseudomonas fluorescens SBW25 in experimental microcosms provides an understanding of the evolutionary ecology and molecular biology of A-L interface biofilm formation. . . .
View in Research Portal

Uncovering behavioural diversity amongst high-strength Pseudomonas spp. surfactants at the limit of liquid surface tension reduction

Kabir, K., Deeni, Y. Y., Hapca, S. M., Moore, L. & Spiers, A. J. (2017) Uncovering behavioural diversity amongst high-strength Pseudomonas spp. surfactants at the limit of liquid surface tension reduction. . . .
View in Research Portal

2016

New insights into the effects of several environmental parameters on the relative fitness of a numerically dominant class of evolved niche specialist

Kuśmierska, A. & Spiers, A. J. (2016) New insights into the effects of several environmental parameters on the relative fitness of a numerically dominant class of evolved niche specialist. . . .
View in Research Portal

Viewing biofilms within the larger context of bacterial aggregations

Moshynets, O. V. & Spiers, A. J. (2016) Viewing biofilms within the larger context of bacterial aggregations. In: Microbial biofilms: importance and applications. Dhanasekaran, D. (ed.), Thajuddin, N. (ed.). p. 3-22. Rijeka: InTech.
View in Research Portal

Conflicting selection alters the trajectory of molecular evolution in a tripartite bacteria-plasmid-phage interaction

Harrison, E., Hall, J. P. J., Paterson, S., Spiers, A. J. & Brockhurst, M. A. (2016) Conflicting selection alters the trajectory of molecular evolution in a tripartite bacteria-plasmid-phage interaction. . . p. 2757–2764. .
View in Research Portal

Biofilm formation and cellulose expression by Bordetella avium 197N, the causative agent of bordetellosis in birds and an opportunistic respiratory pathogen in humans

McLaughlin, K., Folorunso, A. O., Deeni, Y. Y., Foster, D., Gorbatiuk, O., Hapca, S. M., Immoor, C., Koza, A., Mohammed, I., Moshynets, O., Rogalsky, S., Zawadzki, K. & Spiers, A. J. (2016) Biofilm formation and cellulose expression by Bordetella avium 197N, the causative agent of bordetellosis in birds and an opportunistic respiratory pathogen in humans. . . p. 419–430. .
View in Research Portal

Limitations of biosurfactant strength produced by bacteria

Fechtner, J., Cameron, S., Deeni, Y. Y., Hapca, S. M., Kabir, K., Mohammed, I. U. & Spiers, A. J. (2016) Limitations of biosurfactant strength produced by bacteria. In: Biosurfactants: occurrences, applications and research. Upton, C. (ed.). p. 125-148 . Hauppauge, NY: Nova Science Publishers.
View in Research Portal

2015

Plasmid carriage can limit bacteria–phage coevolution

Harrison, E., Truman, J., Wright, R., Spiers, A. J., Paterson, S. & Brockhurst, M. A. (2015) Plasmid carriage can limit bacteria–phage coevolution. . . .
View in Research Portal

A role for glutathione and its biosynthetic genes in Anopheles gambiae insecticide resistance

Abdu, H., Spiers, A. J., Hapca, S. M. & Deeni, Y. Y. (2015) A role for glutathione and its biosynthetic genes in Anopheles gambiae insecticide resistance. . . p. S24. .
View in Research Portal

Environmentally co-occurring mercury resistance plasmids are genetically and phenotypically diverse and confer variable context-dependent fitness effects

Hall, J. P. J., Harrison, E., Lilley, A. K., Paterson, S., Spiers, A. J. & Brockhurst, M. A. (2015) Environmentally co-occurring mercury resistance plasmids are genetically and phenotypically diverse and confer variable context-dependent fitness effects. . . p. 5008-5022. .
View in Research Portal

The evolution of biofilm-forming Wrinkly Spreaders in static microcosms and drip-fed columns selects for subtle differences in wrinkleality and fitness

Udall, Y. C., Deeni, Y. Y., Hapca, S. M., Raikes, D. & Spiers, A. J. (2015) The evolution of biofilm-forming Wrinkly Spreaders in static microcosms and drip-fed columns selects for subtle differences in wrinkleality and fitness. . . .
View in Research Portal

Bacteriophages limit the existence conditions for conjugative plasmids

Harrison, E., Wood, J. A., Dytham, C., Pitchford, J. W., Truman, J., Spiers, A. J., Paterson, S. & Brockhurst, M. A. (2015) Bacteriophages limit the existence conditions for conjugative plasmids. . . .
View in Research Portal

Parallel compensatory evolution stabilizes plasmids across the parasitism-mutualism continuum

Harrison, E., Guymer, D., Spiers, A. J., Paterson, S. & Brockhurst, M. A. (2015) Parallel compensatory evolution stabilizes plasmids across the parasitism-mutualism continuum. . . p. 2034-2039. .
View in Research Portal

Rapid compensatory evolution promotes the survival of conjugative plasmids

Harrison, E., Dytham, C., Hall, J. P. J., Guymer, D., Spiers, A. J., Paterson, S. & Brockhurst, M. A. (2015) Rapid compensatory evolution promotes the survival of conjugative plasmids. . . .
View in Research Portal

2014

Investigating the role of glutathione and glutathione biosynthetic enzymes in the adaptation of Anopheles gambiae to insecticides

Abdu, H. U., Spiers, A. & Deeni, Y. (2014) Investigating the role of glutathione and glutathione biosynthetic enzymes in the adaptation of Anopheles gambiae to insecticides. . . p. S91-S91. .
View in Research Portal

Transparent soil microcosms allow 3D spatial quantification of soil microbiological processes in vivo

Downie, H. F., Valentine, T. A., Otten, W., Spiers, A. J. & Dupuy, L. X. (2014) Transparent soil microcosms allow 3D spatial quantification of soil microbiological processes in vivo. . . .
View in Research Portal

Quorum-quenching activity of the AHL-lactonase from Bacillus licheniformis DAHB1 inhibits vibrio biofilm formation in vitro and reduces shrimp intestinal colonisation and mortality

Vinoj, G., Vaseeharan, B., Thomas, S., Spiers, A. J. & Shanthi, S. (2014) Quorum-quenching activity of the AHL-lactonase from Bacillus licheniformis DAHB1 inhibits vibrio biofilm formation in vitro and reduces shrimp intestinal colonisation and mortality. . . p. 707-715. .
View in Research Portal

Getting Wrinkly Spreaders to demonstrate evolution in schools

Spiers, A. J. (2014) Getting Wrinkly Spreaders to demonstrate evolution in schools. . . p. 301-303. .
View in Research Portal

Predicting the minimum liquid surface tension activity of pseudomonads expressing biosurfactants

Mohammed, I. U., Deeni, Y. Y., Hapca, S. M., McLaughlin, K. & Spiers, A. J. (2014) Predicting the minimum liquid surface tension activity of pseudomonads expressing biosurfactants. . . p. 37–43. .
View in Research Portal

A mechanistic explanation linking adaptive mutation, niche change, and fitness advantage for the Wrinkly Spreader

Spiers, A. J. (2014) A mechanistic explanation linking adaptive mutation, niche change, and fitness advantage for the Wrinkly Spreader. . . .
View in Research Portal

2013

From Winogradsky's column to contemporary research using bacterial microcosms

Moshynets, O., Boretska, M. & Spiers, A. J. (2013) From Winogradsky's column to contemporary research using bacterial microcosms. In: Microcosms: ecology, biological implications and environmental impact. Harris, C. (ed.). Hauppauge, NY : Nova Publishers.
View in Research Portal

Bacterial evolution in simple microcosms

Spiers, A. J. (2013) Bacterial evolution in simple microcosms. In: Microcosms: ecology, biological implications and environmental impact. Harris, C. (ed.). Hauppauge, NY : Nova Publishers.
View in Research Portal

2012

Transparent soil for imaging the rhizosphere

Downie, H. F., Holden, N., Otten, W., Spiers, A. J., Valentine, T. A. & Dupuy, L. X. (2012) Transparent soil for imaging the rhizosphere. . . .
View in Research Portal

Air–liquid interface biofilm formation by psychrotrophic pseudomonads recovered from spoilt meat

Robertson, M., Hapca, S. M., Moshynets, O. & Spiers, A. J. (2012) Air–liquid interface biofilm formation by psychrotrophic pseudomonads recovered from spoilt meat. . . p. 251–259. .
View in Research Portal

The Donaldson review and Scottish Baccalaureates – a model for implementation in schools

Ritchie, M. R., Keith, D., Jones, D., Ramnarine, S. & Spiers, A. (2012) The Donaldson review and Scottish Baccalaureates – a model for implementation in schools. . . p. 99-108. .
View in Research Portal

Cellulose expression in Pseudomonas fluorescens SBW25 and other environmental Pseudomonads

Spiers, A. J., Folorunso, A. O., Zawadzki, K., Deeni, Y. Y., Koza, A. & Moshynets, O. (2012) Cellulose expression in Pseudomonas fluorescens SBW25 and other environmental Pseudomonads. In: Cellulose: medical, pharmaceutical and electronic applications. van de Ven, T. (ed.), Godbout, L. (ed.). Rijeka: InTech.
View in Research Portal

Impact of nano-silver exposure on microbial activity

Morales, V. L., Braga Jr., R. A. & Spiers, A. J. (2012) Impact of nano-silver exposure on microbial activity. . . .
View in Research Portal

2011

The composition and potential impact of the colmation zone on sewer exfiltration

Blackwood, D. J. ., Spiers, A. J., Peter, R. & Gilmour, D. J. (2011) The composition and potential impact of the colmation zone on sewer exfiltration. . . .
View in Research Portal

Up-dating the Cholodny method using PET films to sample microbial communities in soil

Moshynets, O. V., Koza, A., Kordium, V. A. & Spiers, A. J. (2011) Up-dating the Cholodny method using PET films to sample microbial communities in soil. . . p. 199-205. .
View in Research Portal

Environmental modification and niche construction

Koza, A., Moshynets, O., Otten, W. & Spiers, A. J. (2011) Environmental modification and niche construction. . . p. 665–673. .
View in Research Portal

Evolution in a test tube

Green, J. H., Koza, A., Moshynets, O., Pajor, R., Ritchie, M. R. & Spiers, A. J. (2011) Evolution in a test tube. . . p. 54-59. .
View in Research Portal

Surfactants expressed by soil pseudomonads alter local soil-water distribution, suggesting a hydrological role for these compounds

Fechtner, J., Koza, A., Dello Sterpaio, P., Hapca, S. M. & Spiers, A. J. (2011) Surfactants expressed by soil pseudomonads alter local soil-water distribution, suggesting a hydrological role for these compounds. . . p. 50-58. .
View in Research Portal

2010

The phytosphere of Brassica napus L. as a niche for Pseudomonas fluorescens SBW25.

Moshynets, O. V., Shpylova, S. P., Spiers, A. J. & Kosakivska, I. V. (2010) The phytosphere of Brassica napus L. as a niche for Pseudomonas fluorescens SBW25.. . . p. 150-153. .
View in Research Portal

Antagonistic coevolution accelerates molecular evolution

Paterson, S., Vogwill, T., Buckling, A., Benmayor, R., Spiers, A. J., Thomson, N. R., Quail, M., Smith, F., Walker, D., Libberton, B., Fenton, A., Hall, N. & Brockhurst, M. A. (2010) Antagonistic coevolution accelerates molecular evolution. . . p. 275-278. .
View in Research Portal

2009

Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens

Silby, M. W., Cerdeño-Tárraga, A. M., Vernikos, G. S., Giddens, S. R., Jackson, R. W., Preston, G. M., Zhang, X., Moon, C. D., Gehrig, S. M., Godfrey, S. A. C., Knight, C. G., Malone, J. G., Robinson, Z., Spiers, A. J., Harris, S., Challis, G. L., Yaxley, A. M., Harris, D., Seeger, K., Murphy, L., Rutter, S., Squares, R., Quail, M. A., Saunders, E., Mavromatis, K., Brettin, T. S., Bentley, S. D., Hothersall, J., Stephens, E., Thomas, C. M., Parkhill, J., Levy, S. B., Rainey, P. B. & Thomson, N. R. (2009) Genomic and genetic analyses of diversity and plant interactions of Pseudomonas fluorescens. . . .
View in Research Portal

Characterization of a novel air–liquid interface biofilm of Pseudomonas fluorescens SBW25

Koza, A., Hallett, P. D., Moon, C. D. & Spiers, A. J. (2009) Characterization of a novel air–liquid interface biofilm of Pseudomonas fluorescens SBW25. . . p. 1397-1406. .
View in Research Portal

2008

Characterizing the regulation of the Pu promoter in Acinetobacter baylyi ADP1

Huang, W. E., Singer, A. C., Spiers, A. J., Preston, G. M. & Whiteley, A. S. (2008) Characterizing the regulation of the Pu promoter in Acinetobacter baylyi ADP1. . . p. 1668-1680. .
View in Research Portal

The minimum information about a genome sequence (MIGS) specification

Field, D., Garrity, G., Gray, T., Morrison, N., Selengut, J., Sterk, P., Tatusova, T., Thomson, N., Allen, M. J., Angiuoli, S. V., Ashburner, M., Axelrod, N., Baldauf, S., Ballard, S., Boore, J., Cochrane, G., Cole, J., Dawyndt, P., De Vos, P., dePamphilis, C., Edwards, R., Faruque, N., Feldman, R., Gilbert, J., Gilna, P., Glöckner, F. O., Goldstein, P., Guralnick, R., Haft, D., Hancock, D., Hermjakob, H., Hertz-Fowler, C., Hugenholtz, P., Joint, I., Kagan, L., Kane, M., Kennedy, J., Kowalchuk, G., Kottmann, R., Kolker, E., Kravitz, S., Kyrpides, N., Leebens-Mack, J., Lewis, S. E., Li, K., Lister, A. L., Lord, P., Maltsev, N., Markowitz, V., Martiny, J., Methe, B., Mizrachi, I., Moxon, R., Nelson, K., Parkhill, J., Proctor, L., White, O., Sansone, S., Spiers, A. J., Stevens, R., Swift, P., Taylor, C., Tateno, Y., Tett, A., Turner, S., Ussery, D., Vaughan, B., Ward, N., Whetzel, T., San Gil, I., Wilson, G. & Wipat, A. (2008) The minimum information about a genome sequence (MIGS) specification. . . p. 541-547. .
View in Research Portal

Microbial distribution in soils

Young, I. M., Crawford, J. W., Nunan, N., Otten, W. & Spiers, A. J. (2008) Microbial distribution in soils. In: Advances in agronomy. Sparks, D. (ed.). 1st ed., p. 81-121. London: Academic Press.
View in Research Portal

2007

Sequence-based analysis of pQBR103

Tett, A., Spiers, A. J., Crossman, L. C., Ager, D., Ciric, L., Dow, J. M., Fry, J. C., Harris, D., Lilley, A., Oliver, A., Parkhill, J., Quail, M. A., Rainey, P. B., Saunders, N. J., Seeger, K., Snyder, L. A. S., Squares, R., Thomas, C. M., Turner, S. L., Zhang, X., Field, D. & Bailey, M. J. (2007) Sequence-based analysis of pQBR103. . . p. 331-340. .
View in Research Portal

Wrinkly-Spreader fitness in the two-dimensional agar plate microcosm: maladaptation, compensation and ecological success

Spiers, A. J. (2007) Wrinkly-Spreader fitness in the two-dimensional agar plate microcosm: maladaptation, compensation and ecological success. . . .
View in Research Portal

The structure–function relationship of WspR, a Pseudomonas fluorescens response regulator with a GGDEF output domain

Malone, J. G., Williams, R., Christen, M., Jenal, U., Spiers, A. J. & Rainey, P. B. (2007) The structure–function relationship of WspR, a Pseudomonas fluorescens response regulator with a GGDEF output domain. . . p. 980-994. .
View in Research Portal

Adaptive divergence in experimental populations of Pseudomonas fluorescens. III. Mutational origins of wrinkly spreader diversity

Bantinaki, E., Kassen, R., Knight, C. G., Robinson, Z., Spiers, A. J. & Rainey, P. B. (2007) Adaptive divergence in experimental populations of Pseudomonas fluorescens. III. Mutational origins of wrinkly spreader diversity. . . p. 441-453. .
View in Research Portal

Single-Cell Raman spectral profiles of Pseudomonas fluorescens SBW25 reflects in vitro and in planta metabolic history

Huang, W. E., Bailey, M. J., Thompson, I. P., Whiteley, A. S. & Spiers, A. J. (2007) Single-Cell Raman spectral profiles of Pseudomonas fluorescens SBW25 reflects in vitro and in planta metabolic history. . . p. 414-425. .
View in Research Portal

Pseudomonas fluorescens SBW25 biofilm and planktonic cells have differentiable raman spectral profiles

Huang, W. E., Ude, S. & Spiers, A. J. (2007) Pseudomonas fluorescens SBW25 biofilm and planktonic cells have differentiable raman spectral profiles. . . p. 471-474. .
View in Research Portal

The environmental plasmid pQBR103 alters the single-cell raman spectral profile of Pseudomonas fluorescens SBW25

Ude, S., Bailey, M. J., Huang, W. E. & Spiers, A. J. (2007) The environmental plasmid pQBR103 alters the single-cell raman spectral profile of Pseudomonas fluorescens SBW25. . . p. 494-497. .
View in Research Portal

The complete genome of the environmental plasmid pQBR103, its role in bacterial adaptation and the pan-microbial sugar beet phytosphere community genome

Spiers, A. J., Tett, A., Field, D. & Bailey, M. J. (2007) The complete genome of the environmental plasmid pQBR103, its role in bacterial adaptation and the pan-microbial sugar beet phytosphere community genome. . . p. 242-242. .
View in Research Portal

2006

Consideration of future requirements for Raman microbiology as an examplar for the ab initio development of informatics frameworks for emergent OMICS technologies

Huang, W. E. & Spiers, A. J. (2006) Consideration of future requirements for Raman microbiology as an examplar for the ab initio development of informatics frameworks for emergent OMICS technologies. . . p. 238-241. .
View in Research Portal

A survey of A-L biofilm formation and cellulose expression amongst soil and plant-associated Pseudomonas isolates

Spiers, A. J., Arnold, D. L., Moon, C. D. & Timms-Wilson, T. M. (2006) A survey of A-L biofilm formation and cellulose expression amongst soil and plant-associated Pseudomonas isolates. In: Microbial ecology of aerial plant surfaces. Bailey, M. (ed.), Lilley, A. (ed.), Timms-Wilson, T. (ed.), Spencer-Phillips, P. (ed.). p. 121-132. Wallingford: CABI.
View in Research Portal

Adaptive divergence in experimental populations of Pseudomonas fluorescens. II. Role of the GGDEF regulator WspR in evolution and development of the wrinkly spreader phenotype

Goymer, P., Kahn, S. G., Malone, J. G., Gehrig, S. M., Spiers, A. J. & Rainey, P. B. (2006) Adaptive divergence in experimental populations of Pseudomonas fluorescens. II. Role of the GGDEF regulator WspR in evolution and development of the wrinkly spreader phenotype. . . p. 515-526. .
View in Research Portal

Biofilm formation and cellulose expression among diverse environmental Pseudomonas isolates

Ude, S., Arnold, D. L., Moon, C. D., Timms-Wilson, T. & Spiers, A. J. (2006) Biofilm formation and cellulose expression among diverse environmental Pseudomonas isolates. . . p. 1997-2011. .
View in Research Portal

The genetics of phenotypic innovation

Beaumont, H. J., Gehrig, S. M., Kassen, R., Knight, C. G., Malone, J., Spiers, A. J. & Rainey, P. B. (2006) The genetics of phenotypic innovation. In: Prokaryotic diversity: mechanisms and significance. Logan, N. (ed.), Lappin-Scott, H. (ed.), Oyston, P. (ed.). p. 91-104. Cambrdige: Cambridge University Press.
View in Research Portal

2005

The Pseudomonas fluorescens SBW25 wrinkly spreader biofilm requires attachment factor, cellulose fibre and LPS interactions to maintain strength and integrity

Spiers, A. J. & Rainey, P. B. (2005) The Pseudomonas fluorescens SBW25 wrinkly spreader biofilm requires attachment factor, cellulose fibre and LPS interactions to maintain strength and integrity. . . p. 2829-2839. .
View in Research Portal

2003

Pseudomonas in the underworld

Preston, G., Spiers, A., Zhang, X., Jackson, R., Gal, M., Knight, C., Gehrig, S., Malone, J., Moon, C., Godfrey, S., Robinson, Z., Bertrand, N., Field, D. & Rainey, P. (2003) Pseudomonas in the underworld. In: Pseudomonas syringae and related pathogens: biology and genetic. Iacobellis, N. (ed.), Collmer, A. (ed.), Hutcheson, S. (ed.), Mansfield, J. (ed.), Morris, C. (ed.), Murillo, J. (ed.), Schaad, N. (ed.), Stead, D. (ed.), Surico, G. (ed.), Ullrich, M. (ed.). 1 ed., p. 347-353. Dordrecht: Kluwer Academic Publishers.
View in Research Portal

Genes encoding a cellulosic polymer contribute toward the ecological success of Pseudomonas fluorescens SBW25 on plant surfaces

Gal, M., Preston, G. M., Massey, R. C., Spiers, A. J. & Rainey, P. B. (2003) Genes encoding a cellulosic polymer contribute toward the ecological success of Pseudomonas fluorescens SBW25 on plant surfaces. . . p. 3109-3121. .
View in Research Portal

Biofilm formation at the air–liquid interface by the Pseudomonas fluorescens SBW25 wrinkly spreader requires an acetylated form of cellulose

Spiers, A. J., Bohannon, J., Gehrig, S. M. & Rainey, P. B. (2003) Biofilm formation at the air–liquid interface by the Pseudomonas fluorescens SBW25 wrinkly spreader requires an acetylated form of cellulose. . . p. 15-27. .
View in Research Portal

2002

Adaptive divergence in experimental populations of Pseudomonas fluorescens. I. Genetic and phenotypic bases of wrinkly spreader fitness

Spiers, A. J., Kahn, S. G., Bohannon, J., Travisano, M. & Rainey, P. B. (2002) Adaptive divergence in experimental populations of Pseudomonas fluorescens. I. Genetic and phenotypic bases of wrinkly spreader fitness. . . p. 33-46. .
View in Research Portal

Entangled cat

Spiers, A. (2002) Entangled cat. . . .
View in Research Portal

2001

Notes on designing a partial genomic database

Spiers, A. J., Field, D., Bailey, M. & Rainey, P. B. (2001) Notes on designing a partial genomic database. . . p. 247-249. .
View in Research Portal

2000

Artefact

Spiers, A. (2000) Artefact. . . p. 53. .
View in Research Portal

The causes of Pseudomonas diversity

Spiers, A. J., Buckling, A. & Rainey, P. B. (2000) The causes of Pseudomonas diversity. . . p. 2345-2350. .
View in Research Portal

1999

C-terminal interactions between the XerC and XerD site-specific recombinases

Spiers, A. J. & Sherratt, D. J. (1999) C-terminal interactions between the XerC and XerD site-specific recombinases. . . p. 1031-1042. .
View in Research Portal

1998

Just think

Spiers, A. (1998) Just think. . . p. 38. .
View in Research Portal

1997

Relating primary structure to function in the Escherichia coli XerD site-specific recombinase

Spiers, A. J. & Sherratt, D. J. (1997) Relating primary structure to function in the Escherichia coli XerD site-specific recombinase. . . p. 1071-1082. .
View in Research Portal

1993

Regulatory interactions between RepA, an essential replication protein, and the DNA repeats of RepFIB from plasmid P307

Spiers, A. J., Bhana, N. & Bergquist, P. L. (1993) Regulatory interactions between RepA, an essential replication protein, and the DNA repeats of RepFIB from plasmid P307. . . p. 4016-4024. .
View in Research Portal

RepFIB

Gibbs, M. D., Spiers, A. J. & Bergquist, P. L. (1993) RepFIB. . . p. 165-179. .
View in Research Portal

1992

Expression and regulation of the RepA protein of the RepFIB replicon from plasmid P307

Spiers, A. J. & Bergquist, P. L. (1992) Expression and regulation of the RepA protein of the RepFIB replicon from plasmid P307. . . p. 7533-7541. .
View in Research Portal

1989

Nucleotide sequence and replication characteristics of RepFIB, a basic replicon of IncF plasmids

Saul, D., Spiers, A. J., McAnulty, J., Gibbs, M. G., Bergquist, P. L. & Hill, D. F. (1989) Nucleotide sequence and replication characteristics of RepFIB, a basic replicon of IncF plasmids. . . p. 2697-2707. .
View in Research Portal

1987

HLA class III and non-HLA blood genetic markers in Chinese

Serjeantson, S. W., Spiers, A., Ranford, P. & Hawkins, B. (1987) HLA class III and non-HLA blood genetic markers in Chinese. In: Human leucocyte antigens in Chinese. Hawkins, B. (ed.). p. 107-115. Hong Kong: Hong Kong University Press.
View in Research Portal

More Information

Funding

My group's research is currently supported by PhD and visiting PhD consumable fees (i.e. bench fees).

Previous funding includes

  • University of Oxford University Challenge Seed Fund (UCSF) (2001).
  • BBSRC Engineering & Biological Systems (2002-2004) (43/E16689, Recognized Researcher).
  • NERC Research Grant (2002-2004) (NER/T/S/2001/00298, Collaborator).
  • BBSRC Plants & Microbial Sciences (2002-2005) (43/P16688, Recognized Researcher).
  • European Commission Project Quality of Life and Management of Living Resources (2002-2006) (QLK5-CT-2002-00914, Partner 03, Scientific Team Supervision).
  • Initial funding support from the SIMBIOS Centre (2007-2011).
  • NERC Standard Research Grant Joint Award (2010-2013) (NE/H005250/1, UAD Principal Investigator).
  • Royal Society of Edinburgh International Exchange Programme Grant (2012).

 

Esteem

Employment History

Postdoctoral Researcher, Biochemistry, University of Oxford (1994 - 1998).

Postdoctoral Researcher, Plant Sciences, University of Oxford (1998 - 2001).

Departmental Research Fellow, Plant Sciences, University of Oxford (2002 - 2003).

University Research Lecturer, Plant Sciences, University of Oxford (2002 - 2006).

Senior CEH-Oxford Research Fellow, NERC Centre for Ecology and Hydrology, Oxford (2006 - 2007).

Esteem

Councils

NERC Peer Review College (from 2012); Royal Society of Biology in Scotland, Branch Council (Ordinary) member (2016 - 2020).

 

Current Professional Memberships

European Society for Evolutionary Biology, Ordinary member (from 2012); Federation of European Microbiological Societies, Affiliate member (from 2013); Higher Education Academy, Senior Fellow (from 2017); International Society for Microbial Ecology, Ordinary member (from 2006); Microbiological Society, Ordinary member (from 2000). Royal Institution, Full member (from 2009); Royal Society of Biology, Fellow (from 2008); Society for Applied Microbiology, Member (from 2013); and Scottish Alliance for Geoscience Environment and Society, Member (from 2007).

Outreach

Leadership, Management and Administrative Roles / Experience

Environment Theme Leader (from 2016); Theme Leaders Group (from 2016); Research Degrees Advisory Panel (from late 2017); Research and Knowledge Exchange Committee (from 2016); REF Group Champion (from 2016); Health and Safety Subcommittee (from 2014); and University Biological Safety Officer (from 2014).

Programme Leaders Group (from 2016); School Academic Committee (from 2016); Student Voice Programme Committee (from 2016); Deans of Science and Engineering in Scotland Education Group (from 2012 but currently inactive); School Health and Safety Committee (Chair) (from 2014); Genetic Modification Safety Committee (Chair) (from 2014); School Safety Officer (from 2014); School Athena SWAN Self-Assessment Team (from 2015); and Graduate School Postgraduate Student Forum (from 2016).

Meet the rest of the team

Ms Kathryn Cairnie-Lyall

Ms Kathryn Cairnie-Lyall

Division of Engineering and Food Sciences | Placement Tutor

View profile

Dr Boon Chu

Dr Boon Chu

Division of Engineering and Food Sciences | Lecturer

View profile